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Injectable PRF in Non-Surgical Periodontal Treatment

Study acronym: IPRF-PERIO
StatusCompleted
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Start date: Nov 6, 2025 to Jan 29, 2026 Show 6 more changesShow less
    • Trial completed
    • Enrollment increased: 13 → 18 participants
    • Primary completion date changed from estimate of Apr 28, 2026 to Mar 29, 2026
    • Study completion date changed from estimate of May 6, 2026 to May 28, 2026
    • Eligibility criteria expanded, about 13 words
    • Secondary endpoints: details revised at 2 of 4 entries
  2. Eligibility criteria shortened, about 57 wordsv2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study aims to evaluate the clinical and microbiological effects of using injectable Platelet-Rich Fibrin (i-PRF) as an adjunct to non-surgical periodontal therapy (scaling and root planing) in patients with periodontitis. The study uses a split-mouth design where one side of the mouth receives the treatment with i-PRF and the other side receives standard treatment alone. Clinical parameters and bacterial counts will be compared at baseline, 1 month, and 3 months after intervention .
Trial Details
NCT Number NCT07375004
Lead Sponsor Al-Mustansiriyah University
Conditions
(from sponsor)		 Periodontitis, Periodontal Pocket, Alveolar Bone Loss
Related terms Alveolar Bone Loss, Periodontal Pocket, Periodontitis
Enrollment 18 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov