A Prospective, Non-Interventional, Single-Centre Study Assessing the Efficacy of a Holistic Upper Face Treatment With Botulinum Neurotoxin A

The goal of this observational study is to learn about the safety, tolerability, and effectiveness of Letibotulinumtoxin A for the holistic treatment of the upper face in adults under 75 years old with moderate to severe upper facial lines, including glabellar lines, forehead lines, and lateral canthal lines. The main questions it aims to answer are: * Does Letibotulinumtoxin A safely and effectively reduce the severity of glabellar lines, forehead lines, and lateral canthal lines in adults under 75? * How well is the treatment tolerated in everyday clinical practice? * What is the patient satisfaction with holistic upper face treatment using Letibotulinumtoxin A? Participants will: * receive Letibotulinumtoxin A injections in the upper face, including glabellar lines, forehead lines, and lateral canthal lines. * be observed and followed up to assess the severity of wrinkles, duration of effect, and patient satisfaction. * report any adverse effects experienced during or after treatment.

NCT Number	NCT07374965
Lead Sponsor	Yuvell Collaborators: Croma-Pharma GmbH
Conditions	Glabellar Lines, Forehead Lines, Crow's Feet, Canthal Lines
Enrollment	20 participants
Start Date	2024-01-29
Primary Completion	2024-05-16 (estimated)
Study Completion	2024-09-09 (estimated)
Updated on ClinicalTrials.gov	2026-01-29