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Safety of Perioperative Anticoagulation Management in People With Active Cancer Undergoing Cancer-Related Surgery or Procedures (ACE-HIGH Study)

Study acronym: ACE-HIGH
StatusRecruiting
PhaseNot applicable
Started2026-05-05
View on ClinicalTrials.gov ↗

Amendment history

2026-09-03
Study Status, Contacts/Locations v2
Recruitment opened
Start dateestimated 2026-03→confirmed 2026-05-05
Study sites0→1
2026-02-05
Study Status v1
Start date2026-01→2026-03
2026-01-20
Original filing
The purpose of this study is to help find how safe current practices are when managing blood thinners in people with cancer who are having surgery or medical procedures. Investigators will also measure how often bleeding or clotting problems happen in this setting. The goal is to use this information to improve future care and reduce these risks for patients. This study will determine whether contemporary practices can be safely applied to cancer patients, and also evaluate the blood thinner level left over in patient's body at the time of surgery.
Trial Details
NCT Number NCT07372716
Lead Sponsor Ottawa Hospital Research Institute
Conditions Thrombosis, Cancer, Thrombosis, Deep Vein, Atrial Fibrillation (AF), Venous Thromboembolic Event, Bleeding
Enrollment 700 participants
Start Date 2026-05-05
Primary Completion 2030-12 (estimated)
Study Completion 2031-12 (estimated)
Updated on ClinicalTrials.gov 2026-09-08