Effect of Rutin on Inflammation Pathways in Ulcerative Colitis Patients

This study evaluates the therapeutic role of Rutin (a plant-derived flavonoid) in reducing the severity of Ulcerative Colitis (UC). The study investigates whether Rutin can decrease intestinal inflammation and improve clinical symptoms by inhibiting the NLRP3 inflammasome signaling pathway, which is activated by oxidative stress in the colon.

NCT Number	NCT07370220
Lead Sponsor	Benha University
Conditions	Ulcerative Colitis
Enrollment	60 participants
Start Date	2025-02-22
Primary Completion	2025-05-25 (estimated)
Study Completion	2025-11-15 (estimated)
Updated on ClinicalTrials.gov	2026-01-27