Clinical Trial

Association of Prognostic Nutritional Index and Controlling Nutritional Status Score With ST Elevation Myocardial Infarction

Completed
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Summary
It is well known that malnutrition is a prognostic risk factor in chronic heart failure (CHF). Weight loss and the development of cardiac cachexia are associated with poor prognosis in CHF. However, objective indices such as the Prognostic Nutrition Index (PNI) and Controlling Nutritional Status (CONUT) have been developed and are widely used today to assess nutritional status. The CONUT index is an effective scoring system for monitoring pre- and post-hospital malnutrition status and is measured by serum albumin level, total cholesterol (TC), and lymphocyte count. PNI, calculated from serum albumin level and lymphocyte count, is another formula reflecting nutritional status and is well known to be associated with the risk of perioperative complications, especially in surgical patients. Only simple blood biomarkers are required to determine these two indices. The aim of this study is to evaluate the effect of nutritional status at admission, assessed by two objective nutritional indices, CONUT and PNI, on the outcomes of STEMI (ST elevation myocardial infarction) patients during a median follow-up period of two years.
Trial Details
NCT Number NCT07369037
Lead Sponsor Muğla Sıtkı Koçman University
Conditions CONUT Score, ST Elevation (STEMI) Myocardial Infarction, Mortality
Enrollment 1,000 participants
Start Date 2022-01-01
Primary Completion 2024-12-31 (estimated)
Study Completion 2025-03-01 (estimated)
Updated on ClinicalTrials.gov 2026-01-27