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Vagus Nerve Stimulation Effect in Frozen Shoulder Treatment

StatusRecruiting
PhaseNot applicable
Started2026-02-02
View on ClinicalTrials.gov ↗

Amendment history

2026-02-02
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2026-02-15→confirmed 2026-02-02
Study sitesdetails revised at 1 of 1 site
2026-01-26
minor
Study Status, Sponsor/Collaborators v1
Re-verified, no change to tracked fields
2026-01-20
minor
Original filing
The goal of this clinical trial is to learn if the addition of transcutaneous vagus nerve stimulation (tVNS) to exercise is effective in improving pain, shoulder function, shoulder range of motion, and psychological factors in adults with frozen shoulder. The main questions this study aims to answer are: Does adding tVNS to exercise reduce shoulder pain ? Does adding tVNS to exercise improve shoulder function and shoulder range of motion? Does adding tVNS to exercise improve psychological factors ? Does adding tVNS to exercise improve patient satisfaction? Researchers will compare the effect of active tVNS added to exercise with sham-controlled tVNS added to exercise to determine whether adding tVNS provides additional benefits in the management of frozen shoulder. Participants will: Receive active tVNS plus exercise therapy or sham-controlled tVNS plus exercise therapy. Attend supervised rehabilitation sessions 3 times per week for 6 weeks. Perform a home exercise program as instructed by the study physiotherapist.
Trial Details
NCT Number NCT07368751
Lead Sponsor Istanbul University - Cerrahpasa
Conditions Frozen Shoulder
Enrollment 40 participants
Start Date 2026-02-02
Primary Completion 2027-02-15 (estimated)
Study Completion 2027-03-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-04