This record was last updated May 28, 2026 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized controlled trial aims to compare the efficacy and safety of reboot surgery versus conventional full house FESS in patients with refractory CRSwNP, focusing on:
1\. Primary Outcome:
* Compare 24-month recurrence rates (defined as endoscopic polyp score ≥2) 2. Secondary Outcomes:
* Recurrence-free survival (time to first recurrence), Quality of life improvement (SNOT-22 scores), Reduction in systemic corticosteroid use, Complication rates (synechiae, bleeding, infection) and Cost-effectiveness of each approach
Protocol Amendment History
1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-18.