Preoperative Risk Stratification in Endometrial Cancer for Tailoring Lymph Node Staging

The goal of this observational study is to evaluaty the accuracy of current risk stratification of patients with endometrial cancer and to redefine lymph node staging recommendations based on real-world clinical data. The main question it aims to answer is: Is there any group of patients who doesn't need lymph node staging for proper indication of adjuvant treatment? Participants are note taking any intervention. They are treated according to current standard of care and followed 3-years after primary surgery.

NCT Number	NCT07368205
Lead Sponsor	University Hospital Hradec Kralove
Conditions	Endometrial Cancer
Enrollment	350 participants
Start Date	2026-02-15
Primary Completion	2028-02 (estimated)
Study Completion	2031-02 (estimated)
Updated on ClinicalTrials.gov	2026-05-22