Clinical Trial

Dimensional Changes of the Keratinized Mucosa in Edentulous Ridges Following Accordian Technique Versus Conventional Free Gingival Grafts

Completed
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Summary
Inadequacy of the attached keratinized tissue (\<2 mm) affects the long-term maintenance of prostheses and implants due to poor oral hygiene, plaque accumulation, inflammation, bleeding on probing, gingival recession , attachment loss, and crestal bone loss .Consequently, keratinized tissue augmentation is considered to compensate for keratinized attached gingival width inadequacy. Lack of keratinized tissue (KT) or KT with a narrow width (≤2 mm) compromise the long-term maintenance of peri-implant tissue health . Peri-implantitis was more frequently detected at dental implants sites with reduced width of KT than at those with adequate KT width. Free gingival graft (FGG) is regarded as an efficient method with significant clinical application . However, following harvesting larger grafts, some limitations arise in the donor site. Extensive palatal wound may cause discomfort and morbidity for the patient, the rugae area is unsuitable for graft material and the greater palatine artery will be of a great concern.
Protocol Amendment History 2 changes
critical Trial completed 2026-08-13
notable Primary completion pushed: 2026-01-30 -> 2026-03-01 2026-08-13
Trial Details
NCT Number NCT07365865
Lead Sponsor Cairo University
Conditions Deficient Keratinized Mucosa, Healthy
Enrollment 36 participants
Start Date 2024-08-14
Primary Completion 2026-03-01 (estimated)
Study Completion 2026-03-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-12