Clinical Trial

Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases

Study acronym: CEUSON
Recruiting
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Summary
This study is an investigator-initiated, randomized controlled trial enrolling patients with colorectal liver metastases. The objectives are to evaluate the safety and efficacy of contrast-enhanced ultrasound (CEUS)-mediated sonoporation as a potential therapeutic intervention and to investigate whether sonoporation can modulate the tumor microenvironment toward a more immune-active state
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-16.
Status change: Not Yet Recruiting → Recruiting 2026-02-24
Trial Details
NCT Number NCT07365527
Lead Sponsor Zealand University Hospital
Collaborators: Rigshospitalet, Denmark
Conditions Liver Metastases From Colorectal Cancer
Enrollment 48 participants
Start Date 2026-02-25
Primary Completion 2027-01-15 (estimated)
Study Completion 2027-01-15 (estimated)
Updated on ClinicalTrials.gov 2026-02-27