Clinical Trial

An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

Name: An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH) — clinical trial record (NCT07365332)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: IMPROVE-PAH

Recruiting Phase 3

View on ClinicalTrials.gov →

Summary

This is an adaptive, 2-part, randomized, multicenter, double-blind, placebo-controlled, parallel-group study designed to evaluate the efficacy and safety of IKT-001 in adult participants with WHO Group 1 PAH.

Protocol Amendment History 1 change

critical Recruitment opened 2026-05-13

Trial Details

NCT Number	NCT07365332
Lead Sponsor	Inhibikase Therapeutics
Conditions	Pulmonary Arterial Hypertension
Enrollment	486 participants
Start Date	2026-04-23
Primary Completion	2029-06 (estimated)
Study Completion	2029-12 (estimated)
Updated on ClinicalTrials.gov	2026-05-12