Clinical Trial

Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma

Study acronym: AFGBMBiop
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The objective of this clinical trial is to investigate the effects of Salovum®, an egg yolk powder enriched with the endogenous protein antisecretory factor, in participants undergoing diagnostic biopsies for suspected glioblastoma. The primary questions the trial seeks to answer are: * Will Salovum® reduce intratumoral pressure? * Will Salovum® influence the release of inflammatory cytokines from tumor tissue? Additionally, the study will investigate the impact of Salovum® on intratumoral partial oxygen pressure and tumor volume. Researchers will: * Place probes for measuring intratumoral pressure, microdialysis, and partial oxygen pressure during a standard biopsy procedure. * Compare measurements from participants before and during ingestion of Salovum®. Participants will: * Have probes implanted during a surgical biopsy. * Ingest Salovum® 24 to 72 hours after the procedure.
Trial Details
NCT Number NCT07364786
Lead Sponsor Peter Siesjö
Collaborators: Lund University, Region Skane
Conditions Glioblastoma
Enrollment 10 participants
Start Date 2024-10-07
Primary Completion 2026-10 (estimated)
Study Completion 2026-11 (estimated)
Updated on ClinicalTrials.gov 2026-01-23