Clinical Trial

Efficacy and Safety of Radiotherapy Combined With Tislelizumab and Anlotinib in the Treatment of Hepatocellular Carcinoma Complicated With Portal Vein Tumor Thrombus

Not Yet Recruiting Phase 2
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Summary
For HCC patients with PVTT who the researchers believe can benefit from radiotherapy combined with tislelizumab and anlotinib, informed consent forms will be signed, and then they will receive the study treatment and be followed up. The research design is as follows: First, radiotherapy was administered. Three days ±1 day after the start of radiotherapy, tislelizumab and anlotinib treatment were initiated. Each cycle was three weeks, and the treatment continued until no toxicity was acceptable or clinical benefits were lost (evaluated by the researcher based on imaging, biochemical indicators, and the patient's clinical status).
Trial Details
NCT Number NCT07363512
Lead Sponsor Henan Cancer Hospital
Conditions HCC - Hepatocellular Carcinoma
Enrollment 27 participants
Start Date 2026-01-05
Primary Completion 2028-03 (estimated)
Study Completion 2028-11 (estimated)
Updated on ClinicalTrials.gov 2026-01-23