Clinical Trial

A Phase Ⅰ/Ⅱa Clinical Study of GEN-725 in Combination With Dositinib

Name: A Phase Ⅰ/Ⅱa Clinical Study of GEN-725 in Combination With Dositinib — clinical trial record (NCT07362940)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting Phase 1/2

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Summary

This is an open-label phase I/phase II clinical study designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GEN-725 in combination with Dositinib in participants with locally advanced or metastatic EGFR-mutant non-small cell lung cancer.

Trial Details

NCT Number	NCT07362940
Lead Sponsor	Henan Genuine Biotech Co., Ltd.
Conditions	Non-Small Cell Lung Cancer
Enrollment	110 participants
Start Date	2025-11-27
Primary Completion	2027-07-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-01-23