BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia

The Biceps Femoris Short Head (BiFeS) block is a new fascial plane block technique targeting the sensory innervation of the posterolateral capsule of the knee while preserving motor function. The aim of this study is to evaluate the postoperative analgesic efficacy of the BiFeS block combined with the adductor canal block (ACB) in patients undergoing total knee arthroplasty, compared to ACB + iPACK block. The study is planned as a prospective, randomized, double-blind, parallel two-group trial. Patients will be randomized in a 1:1 ratio to receive ACB + iPACK (Group A) or ACB + BiFeS (Group B). Postoperative pain scores (VAS), opioid consumption, early mobilization, and quality of recovery (QoR-15) outcomes will be compared.

NCT Number	NCT07360392
Lead Sponsor	Amasya University
Conditions	Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia, Regional
Enrollment	88 participants
Start Date	2026-04-20
Primary Completion	2027-03-01 (estimated)
Study Completion	2027-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-22