Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study

The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women. The main questions it seeks to answer are: * Is the objective cure rate for vaginal mesh surgery non-inferior to that of the abdominal approach? * Is the use of vaginal mesh as safe as abdominal mesh?

NCT Number	NCT07359755
Lead Sponsor	University of Sao Paulo General Hospital
Conditions	Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Mesh Reinforcement, Vaginal Apex/Uterine Prolapse
Enrollment	86 participants
Start Date	2025-09-15
Primary Completion	2027-10 (estimated)
Study Completion	2030-06 (estimated)
Updated on ClinicalTrials.gov	2026-01-22