Clinical Trial

Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation

Recruiting
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Summary
To evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction. Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. Eligible patients will be randomly allocated into two groups. Clinical photographs: Clinical photographs will be taken at baseline, 1 and 6 months postoperatively. Intervention Group (Group A): Microneedling will be done with application of Platelet Rich Plasma for depigmentation. Control Group (Group B): microneedling will be done alone for depigmentation.
Trial Details
NCT Number NCT07359339
Lead Sponsor Cairo University
Conditions Gingival Pigmentation
Enrollment 32 participants
Start Date 2025-10-01
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-11-10 (estimated)
Updated on ClinicalTrials.gov 2026-01-22