Clinical Trial

A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine

Active, Not Recruiting
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Record status
This record was last updated January 22, 2026 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.
Summary
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine. Participants with deep carious lesions will be allocated to one of two treatment protocols, and clinical and radiographic assessments will be performed to evaluate outcomes. The findings of this study may provide evidence on whether diode laser pre-treatment offers additional clinical benefits when used prior to Biodentine application in the management of deep caries.
Trial Details
NCT Number NCT07358442
Lead Sponsor Misr International University
Collaborators: National Research Centre, Egypt
Conditions Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
Enrollment 48 participants
Start Date 2025-07-30
Primary Completion 2026-07 (estimated)
Study Completion 2026-07 (estimated)
Updated on ClinicalTrials.gov 2026-01-22