Clinical Trial

CPAP Therapy and Atrial Fibrillation Recurrence in OSA

Study acronym: CPAP-AF
Active, Not Recruiting
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Summary
Obstructive sleep apnea (OSA) is a major modifiable risk factor for atrial fibrillation (AF). Continuous positive airway pressure (CPAP) therapy has been shown to improve cardiovascular outcomes; however, real-world data on its effect on AF recurrence remain limited. This prospective cohort study aims to evaluate the association between objective CPAP adherence and the risk of AF recurrence in patients with moderate-to-severe OSA and a history of paroxysmal AF. Patients will be followed for 12 months, with AF recurrence assessed using electrocardiography and Holter monitoring.
Trial Details
NCT Number NCT07358429
Lead Sponsor Medical University of Sofia
Conditions Obstructive Sleep Apnea (OSA), Atrial Fibrillation (Paroxysmal)
Enrollment 91 participants
Start Date 2024-09-01
Primary Completion 2025-11-30 (estimated)
Study Completion 2027-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-22