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Effectiveness of Large Language Model-Based Chatbot Among Female University Stdents in Improving HPV Vaccine Awareness, Intention and Vaccination Rates

StatusNot Yet Recruiting
PhaseNot applicable
Started
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Record History

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  1. Primary endpoint(s) modifiedv2 Show 6 more changesShow less
    • Enrollment reduced: 36000 → 18000 participants
    • Start date: Jan 10, 2026 to Apr 1, 2026
    • Eligibility criteria shortened, about 10 words
    • Secondary endpoints revised (2)
    • Collaborators shortened, about 7 words
    • Study title expanded, about 4 words
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This is an interventional study targeting female university students. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates. The secondary objectives are to evaluate the effectiveness in improving vaccine awareness and vaccination intention. All participants will be enrolled and randomly assigned to four groups: (1) vaccine chatbot plus scientific videos, (2) vaccine chatbot only, (3) scientific videos only, and (4) a control group (no intervention). The chatbot will provide immediate, validated answers to participants' HPV vaccine-related questions. The scientific videos will cover content related to HPV vaccine safety, efficacy, and other relevant information. The study will compare changes in HPV vaccine awareness, vaccination intention, and vaccination behavior between the intervention groups and the control group after the intervention to evaluate whether the three intervention strategies enhance HPV vaccine awareness, vaccination intention, and vaccination uptake.
Trial Details
NCT Number NCT07351604
Lead Sponsor Xiamen University
Conditions
(from sponsor)		 HPV Vaccination Rates, HPV Vaccine Awareness, HPV Vaccination Intention
Enrollment 18,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov