Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining

Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with a placebo mouth rinse. The primary outcomes evaluated were changes in i) bacterial biofilm accumulation, ii) gingival inflammation, and iii) tooth staining. Secondarily, patient's satisfaction and perspective after the use of these formulations was assessed.

NCT Number	NCT07351370
Lead Sponsor	Dental School
Conditions	Mouthwashes, Chlorhexidine, Dental Plaque, Gingival and Periodontal Disease, Randomized Controlled Trial
Enrollment	81 participants
Start Date	2022-01-15
Primary Completion	2022-07-20 (estimated)
Study Completion	2022-07-20 (estimated)
Updated on ClinicalTrials.gov	2026-04-08