Clinical Trial

The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar

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Summary
Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus while delayed post operative complications are mostly seen on the distal surface of second molar due to distal bone loss which include prolonged sensitivity due to increased periodontal pocket depth, gingival recession and root exposure. When PRF clot is given in wound, it causes alterations of the cellular ratios in the wound blood clot, leading to replacement of blood cells with Platelets and growth factors stimulating all phases of healing which will improve the immidiate and delayed post operative complications The purpose of present study is to compare the clinical outcomes in the treatment of senstivity and periodontal pockets at the distal aspect of second molar following surgical extraction of impacted third molar using PRF or Blood clot alone.
Trial Details
NCT Number NCT07351279
Lead Sponsor University of Health Sciences Lahore
Conditions Third Molar Impaction, Surgical Extraction of Impacted Third Molars
Enrollment 56 participants
Start Date 2026-02
Primary Completion 2027-07 (estimated)
Study Completion 2028-02 (estimated)
Updated on ClinicalTrials.gov 2026-01-20