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Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty

Study acronym: BALIA
StatusRecruiting
PhasePhase 4
Started2026-03-05
View on ClinicalTrials.gov ↗

Amendment history

2026-05-04
Study Status, Contacts/Locations v1
Recruitment opened
Start dateestimated 2026-03-01→confirmed 2026-03-05
Study sitesdetails revised at 1 of 1 site
2026-01-13
Original filing
Region Skane
146 trials monitored
See 5 trials at risk
The aim of this clinical randomized trial is to compare local infiltration analgesia (LIA) alone versus the combination of LIA with saphenous nerve (SN) block, block of the nerve to vastus medialis (NVM), and anterior femoral cutaneous nerve (AFCN) block in participants undergoing total knee arthroplasty (TKA). The primary outcome is pain intensity, measured using the Numerical Rating Scale (NRS) at multiple time points after surgery. Secondary outcomes include opioid consumption, time to mobilization, postoperative nausea and vomiting, length of hospital stay, neurological complications and differences in opioid consumption and NRS pain scores between general and spinal anesthesia.
Trial Details
NCT Number NCT07350252
Lead Sponsor Region Skane
Collaborators: Greta and Johan Kock Foundation
Conditions Osteo Arthritis of the Knee
Enrollment 200 participants
Start Date 2026-03-05
Primary Completion 2027-03-01 (estimated)
Study Completion 2027-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-08