Pentoxifylline in Patients With Ulcerative Colitis

Ulcerative colitis (UC) is a persistent, idiopathic form of inflammatory bowel disease (IBD) marked by uninterrupted inflammation of the colon's mucosal lining, usually starting at the rectum and progressing proximally in a continuous manner. It manifests clinically with recurrent episodes of abdominal pain, bloody diarrhea, urgency, tenesmus, and weight loss. The precise cause of UC is still unknown; however, it is thought to arise from a multifactorial interaction involving genetic susceptibility, immune system dysregulation, disturbances in gut microbiota composition, and various environmental factors.

NCT Number	NCT07349472
Lead Sponsor	Ihab Elsayed Hassan
Conditions	Inflammatory Bowel Diseases
Enrollment	60 participants
Start Date	2026-01-20
Primary Completion	2027-01-20 (estimated)
Study Completion	2027-02-20 (estimated)
Updated on ClinicalTrials.gov	2026-04-15