Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital. Some participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.

NCT Number	NCT07347925
Lead Sponsor	Future University in Egypt
Conditions	Heart Failure
Enrollment	140 participants
Start Date	2026-01-10
Primary Completion	2026-04-15 (estimated)
Study Completion	2026-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-16