Clinical Trial

Functional Rehabilitation Effects on Exercise-induced Hypoalgesia in Chronic Low Back Pain

Study acronym: ALGO_LC
Enrolling by Invitation
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Summary
Chronic low back pain is a prevalent condition characterized by persistent pain and associated physical and psychosocial limitations. Physical exercise is currently considered a primary treatment to promote positive outcomes in individuals with chronic low back pain. However, pain itself represents a major barrier to regular participation in physical activity. In healthy individuals, exercise induces hypoalgesia, reflected by an increase in pain detection thresholds following physical activity. Enhancing exercise-induced hypoalgesia may promote adherence to regular physical activity in individuals with chronic low back pain. Previous research suggests that regular physical activity may facilitate exercise-induced hypoalgesia through physiological responses associated with exercise that are influenced by physical activity levels. Therefore, interventions centered on physical activity may enhance exercise-induced hypoalgesia in individuals with chronic low back pain, potentially contributing to pain reduction and increased engagement in physical activity. The primary objective of this exploratory study is to evaluate the effects of a four-week functional rehabilitation program, with physical activity as its main component, on exercise-induced hypoalgesia in individuals with chronic low back pain
Trial Details
NCT Number NCT07347457
Lead Sponsor Clinique de la Mitterie
Collaborators: Clinique les Peupliers
Conditions Low Back Pain
Enrollment 51 participants
Start Date 2025-11-14
Primary Completion 2026-01-07 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-16