Clinical Trial

Role of Circulating MicroRNAs in Differentiating Psychological Disorders Among Women With Chronic Toxoplasmosis

Recruiting
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Record status
This record was last updated January 16, 2026 (before its estimated February 2026 completion). Its status may not reflect the trial's current state.
Summary
Chronic Toxoplasma gondii (T. gondii) infection is a widespread condition that can negatively affect brain function and is considered a risk factor for various psychiatric conditions, including depression and schizophrenia. This prospective observational study aims to investigate the expression levels of specific circulating microRNAs (miRNAs) in women diagnosed with schizophrenia, major depressive disorder, or bipolar disorder who also have chronic toxoplasmosis. By comparing these levels to patients without the infection, the study seeks to determine if these miRNAs can serve as biological markers to help differentiate between specific psychological disorders and identify the impact of chronic toxoplasmosis on mental health.
Trial Details
NCT Number NCT07346833
Lead Sponsor Benha University
Conditions Toxoplasmosis
Enrollment 55 participants
Start Date 2025-11-20
Primary Completion 2026-02 (estimated)
Study Completion 2026-04 (estimated)
Updated on ClinicalTrials.gov 2026-01-16