Clinical Trial

Augmentation of Peri-implant Keratinized Mucosa Using a Combination of Free Gingival Graft Strip With Platelet-Rich Fibrin

Completed
View on ClinicalTrials.gov →
Summary
This clinical trial aims to evaluate the clinical effectiveness of combining a strip free gingival graft (sFGG) with Platelet-Rich Fibrin (PRF) for increasing keratinized mucosa around dental implants. The study compares this combined technique with the conventional free gingival graft (FGG) method through three primary objectives: 1. comparing the increase in keratinized mucosal height at immediate post-op, 1, 3, and 6 months; 2. assessing post-operative pain levels at 1, 3, 7, and 14 days; 3. evaluating soft tissue aesthetic outcomes at 6 months post-surgery.
Protocol Amendment History 5 changes
critical Trial completed 2026-07-21
critical Primary endpoint(s) modified 2026-07-21
notable Sponsor changed: Nguyen Van Khuong -> University of Medicine and Pharmacy at Ho Chi Minh City 2026-07-21
notable Primary completion pushed: 2026-06-01 -> 2026-07-16 2026-07-21
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-04-23
Trial Details
NCT Number NCT07346391
Lead Sponsor University of Medicine and Pharmacy at Ho Chi Minh City
Conditions Dental Implants
Enrollment 22 participants
Start Date 2025-12-24
Primary Completion 2026-07-16 (estimated)
Study Completion 2026-07-16 (estimated)
Updated on ClinicalTrials.gov 2026-07-20