Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock

Cardiogenic shock is a life-threatening condition characterized by inadequate cardiac output, leading to organ hypoperfusion and high mortality. Maintaining mean arterial pressure (MAP) is crucial, but standard targets may be insufficient due to venous congestion. Central venous pressure (CVP) can help assess effective perfusion pressure. This study investigates whether a personalized MAP target adjusted by CVP improves organ function and survival compared to standard MAP management.

NCT Number	NCT07345559
Lead Sponsor	CMC Ambroise Paré
Conditions	Cardiogenic Shock
Enrollment	406 participants
Start Date	2026-03-26
Primary Completion	2029-07-25 (estimated)
Study Completion	2029-07-25 (estimated)
Updated on ClinicalTrials.gov	2026-04-02