Association Between Autonomic Dysfunction and Choroidal Vascularity Index in Fibromyalgia

Fibromyalgia is frequently accompanied by autonomic nervous system dysfunction, often characterized by sympathetic predominance. Alterations in ocular microcirculation have been reported in the presence of autonomic dysfunction, including potential reductions in choroidal vascular parameters. This observational study aims to examine the association between autonomic symptom burden and the choroidal vascularity index (CVI), a quantitative marker of choroidal vascular structure derived from optical coherence tomography (OCT), in individuals with fibromyalgia compared with age- and sex-matched healthy controls.

NCT Number	NCT07345546
Lead Sponsor	Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Conditions	Fibromyalgia, Autonomic Dysfunction
Enrollment	80 participants
Start Date	2025-10-20
Primary Completion	2025-12-18 (estimated)
Study Completion	2025-12-19 (estimated)
Updated on ClinicalTrials.gov	2026-04-08