Clinical Trial

The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Facial Erythema and Other Skin Parameters

Study acronym: TO-COSKIN4
Not Yet Recruiting
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Summary
The aim of this study is to compare the effects of 16 weeks of daily dietary supplementation with two investigational products containing collagen, methylsulfonylmethane (MSM), and vitamin C on skin parameters in comparison to a placebo product. The study will be conducted in healthy human subjects with visible facial erythema and telangiectasiae (cheeks), stable for ≥3 months, without active rosacea. The primary objective is to demonstrate beneficial effects of the investigational products on facial erythema. The secondary objective is to evaluate the effect of the investigational products on facial telangiectasiae severity. Other skin parameters will be assessed as supportive endpoints, and differences in efficacy between the two investigational formulations will also be evaluated.
Trial Details
NCT Number NCT07345195
Lead Sponsor VIST - Faculty of Applied Sciences
Collaborators: Tosla d.o.o., Slovenian Research Agency
Conditions Erythema, Telangiectasis, Skin Redness
Enrollment 90 participants
Start Date 2026-01
Primary Completion 2026-09 (estimated)
Study Completion 2026-11 (estimated)
Updated on ClinicalTrials.gov 2026-01-15