Burning Mouth Syndrome: Effects of Occlusal Splint Therapy

Burning Mouth Syndrome (BMS) causes chronic oral pain and significantly affects quality of life. Effective treatments are limited and often provide only temporary relief. This prospective N-of-1 study evaluates the effect of an intraoral Essix appliance on pain intensity and salivary secretion in patients with BMS. Saliva samples are collected and analysed for volume and composition.

NCT Number	NCT07344909
Lead Sponsor	Malmö University
Conditions	Burning Mouth Syndrome, Orofacial Pain, Mouth Dryness
Enrollment	12 participants
Start Date	2026-01-15
Primary Completion	2026-11-01 (estimated)
Study Completion	2027-11-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-15