Clinical Trial

Adaptive Stereotactic Radiotherapy for Localized Prostate Cancer

Study acronym: SPAR
Recruiting
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Summary
This study evaluates whether adaptive stereotactic body radiotherapy (SBRT) provides dosimetric advantages compared to non-adaptive SBRT in localized prostate cancer. Five low-dose CT scans are performed before each SBRT session to assess anatomical variations (bladder filling, rectal volume) and determine if a dosimetric recalculation would have been required. The study also evaluates cumulative dose to organs at risk, patient-reported quality of life over 24 months, and overall and recurrence-free survival.
Trial Details
NCT Number NCT07344844
Lead Sponsor Clinique Sainte Clotilde
Conditions Prostate Cancer (Adenocarcinoma)
Enrollment 100 participants
Start Date 2025-11-18
Primary Completion 2029-03-01 (estimated)
Study Completion 2029-05-01 (estimated)
Updated on ClinicalTrials.gov 2026-01-15