Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function

Local vibration is a non-invasive neuromuscular stimulation modality used in training and rehabilitation for its effects on neuromuscular function, particularly its ability to induce nervous adaptations. Its passive application is particularly useful in cases of motor deficit or immobilization. Several studies, including our own, have shown that vibration protocols over several weeks can induce significant gains in muscle strength, particularly in the knee extensors. However, the parameters of application remain heterogeneous, particularly with regard to the duration of the interventions. With this in mind, a prospective controlled study is being conducted in healthy subjects, comparing four modalities of local vibration intervention targeting the knee extensors: an intensive vibration protocol over 5 consecutive days (1 session of 30 or 60 minutes per day) and a protocol spread over 4 weeks at a rate of 3 weekly sessions of 30 or 60 minutes). The objective is to evaluate and compare their immediate and delayed effects on force production and corticospinal properties. The results of this study will thus help optimize recommendations regarding the use of local vibration in muscle strengthening and neuromuscular reconditioning strategies.

NCT Number	NCT07344298
Lead Sponsor	Centre Hospitalier Universitaire de Saint Etienne Collaborators: Laboratoire Interuniversitaire de Biologie de la Motricité
Conditions	Healthy Volonteers
Enrollment	72 participants
Start Date	2026-03-23
Primary Completion	2028-01-22 (estimated)
Study Completion	2028-01-22 (estimated)
Updated on ClinicalTrials.gov	2026-03-27