THE EFFECT OF ENDODONTIC TREATMENT ON CARDIOVASCULAR RISK BIOMARKERS IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE

Study subjects were obtained from the pool of OPD patients in the Department of Conservative Dentistry and Endodontics, PGIDS, Rohtak, and the Department of Cardiology, PGIMS, Rohtak. Baseline clinical, radiographic, and laboratory parameters (hsCRP and IL-6) were recorded. Patients were then randomly allocated to one of the two groups. In the test group, single-sitting root canal treatment was performed immediately, while in the control group, delayed endodontic intervention (after 3 months) was performed after three months. Clinical and laboratory parameters were again assessed at the end of 3 months in both groups. hsCRP and IL-6 indices were again done in the delayed treatment group after 3 months of root canal treatment.

NCT Number	NCT07343804
Lead Sponsor	Postgraduate Institute of Dental Sciences Rohtak
Conditions	Cardiovascular Disease Risk Factor, Periapical Periodontitis
Enrollment	80 participants
Start Date	2025-11-01
Primary Completion	2026-02 (estimated)
Study Completion	2026-03 (estimated)
Updated on ClinicalTrials.gov	2026-01-15