Clinical Trial

Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery

Recruiting
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Summary
The goal of this clinical trial is to study whether researchers can create a patient-specific tumor system, called a culture vessel, in a timely manner and determine if it can predict how someone will respond to a specific therapy. Participants will: * Undergo a research biopsy * Take pembrolizumab per standard of care prior to surgery
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2026-01-14; most recent amendment 2026-04-20.
Status change: Not Yet Recruiting → Recruiting 2026-02-27
Trial Details
NCT Number NCT07343596
Lead Sponsor University of Wisconsin, Madison
Conditions Oral Cavity Cancer
Enrollment 20 participants
Start Date 2026-04-15
Primary Completion 2027-12 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-10