Clinical Trial

OCT Angiography Drived Alterations in Thyroid-associated Orbitopathy

Study acronym: TAO
Completed
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Summary
The aim of this observational study is to evaluate retinal microvascular alterations in patients with thyroid-associated orbitopathy (TAO) using optical coherence tomography angiography (OCTA). The specific objectives are: * To assess the impact of extraocular muscle (EOM) enlargement on vessel density in the superficial and deep retinal capillary plexuses in patients with TAO. * To determine the effect of increased orbital fat volume on superficial and deep retinal vessel density in TAO. * To evaluate the relationship between disease activity, as measured by the Clinical Activity Score (CAS), and retinal microvascular density in patients with TAO.
Trial Details
NCT Number NCT07341347
Lead Sponsor Osijek University Hospital
Conditions Thyroid Associated Orbitopathy
Enrollment 68 participants
Start Date 2024-12-09
Primary Completion 2025-06-15 (estimated)
Study Completion 2025-07-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-14