Clinical Trial

Chemo Brain Prehab Project

Study acronym: CHEMOBRAIN
Not Yet Recruiting
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Summary
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin. A side effect of these drugs is loss of memory, forgetfulness, and general brain fog, which can persist for months after the end of treatment. These symptoms are collectively known as 'chemo-brain'. An existing prehabilitation intervention that has been previously developed will be used, which increases fitness and reduces hospital length of stay in colorectal cancer surgery patients, to try to improve the symptoms of chemo-brain in those undergoing chemotherapy and improve quality of life.
Trial Details
NCT Number NCT07341217
Lead Sponsor Dr. Chris Gaffney
Conditions Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
Enrollment 86 participants
Start Date 2026-01-30
Primary Completion 2027-09-16 (estimated)
Study Completion 2027-09-16 (estimated)
Updated on ClinicalTrials.gov 2026-01-14