Reconstruction of Orbital Floor Blow-out Fractures by Titanium Mesh Versus Autogenous Iliac Graft

Blow-out fractures result from direct blunt impacts to the orbit which causes an immediate rise increase in intra-orbital pressure. Decompression via fracture of the orbital floor then occurs. Motor vehicle accidents are the main cause of orbital trauma. Also, industrial accidents, sports-related facial trauma, and assaults are important causes. Clinical manifestations include ecchymosis, limitation of eye movements resulting in diplopia, enophthalmos. Very rarely, severe pain and nausea immediately after the injury are reported. Radiologic evaluation including computed tomography (CT), plane radiology and magnetic resonance imaging (MRI) are the mainstay diagnostic modalities used for evaluation of cases with orbital trauma. Treatment of the orbital blow-out fractures is aimed at restoring floor continuity, thus providing adequate support for orbital contents preventing their herniation and incarceration, thereby possible subsequent fibrosis of soft tissues most importantly extraocular muscles. Various alloplastic or autogenous grafts are used for reconstruction of orbital blow-out fractures.

NCT Number	NCT07340879
Lead Sponsor	Assiut University
Conditions	Blow-Out Fractures
Enrollment	80 participants
Start Date	2020-05-02
Primary Completion	2023-05-30 (estimated)
Study Completion	2024-05-20 (estimated)
Updated on ClinicalTrials.gov	2026-01-21