Effect of Yellow Light AG Mobile Phone Screen on Dry Eye and Asthenopia.

This study aimed to evaluate the protective effects of yellow-light etching anti-glare (AG) screen on Digital Eye Strain (DES) induced by prolonged video display terminal (VDT) use under dim environment, Based on the proved positive effect of the circular polarization (CP) screen, providing insights for new eye-protection strategy in the highly digital modern era. In a randomized, double-blind controlled trial, 70 eligible volunteers (diopter ≤ -6.0D; anisometropia ≤ 2.0D) were divided into AG+CP or CP only groups. Participants performed a 2-hour e-book reading task using assigned AG+CP or CP only smartphones. Subjects' severity of DES pre- and post-reading were evaluated from two aspects: the degree of dry eye symptoms and asthenopia. Dry eye symptoms indicators (OSDI, TMH, NIBUT, FBUT, CFS, Schirmer I Test) and asthenopia indicators (CVSS17, Bulbar redness, HFC) were measured and compared.

NCT Number	NCT07340359
Lead Sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions	Digital Eye Strain, Computer Vision Syndrome, Dry Eye, Asthenopia
Enrollment	70 participants
Start Date	2026-01-10
Primary Completion	2026-01-21 (estimated)
Study Completion	2026-02-21 (estimated)
Updated on ClinicalTrials.gov	2026-03-05