Study of Gum Tissue Proteins in Smokers vs. Non-smokers After Cleaning

The aim of this study is to evaluate how smoking affects the healing process of the gums after treatment. The researchers will measure the levels of two specific proteins (PLAP-1 and Sclerostin) in the gum fluid of patients with stage II periodontitis. These measurements will be compared between smokers and non-smokers before and after receiving non-surgical periodontal therapy (cleaning and scaling) to see if smoking changes the body's response to treatment.

NCT Number	NCT07339670
Lead Sponsor	Al-Azhar University
Conditions	Smoking ( Cigarette), Periodontitis Stage II
Enrollment	36 participants
Start Date	2024-11-11
Primary Completion	2025-04-11 (estimated)
Study Completion	2025-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-01-14