Probiotics in COPD: Effects on Symptoms, Lung Function, and Inflammation

The goal of this randomized, placebo controlled, double-blind clinical trial is to find out whether a probiotic supplement can help adults with chronic obstructive pulmonary disease (COPD) breathe better and better control their symptoms. The study will try to answer does taking a probiotic supplement, compare with a placebo, reduce shortness of breath, does it improve daily COPD symptoms or change stool patterns by using validated questionnaires; does it affect lung function or inflammation. The results of this study may contribute to a better understanding of the disease, the application of new therapeutic options, and provide a foundation for future research.

NCT Number	NCT07339280
Lead Sponsor	University Hospital of Split Collaborators: Abela Pharmaceuticals, Inc.
Conditions	COPD, COPD (Chronic Obstructive Pulmonary Disease), Probiotic, Probiotic Supplement
Enrollment	60 participants
Start Date	2026-03-08
Primary Completion	2027-09 (estimated)
Study Completion	2030-12 (estimated)
Updated on ClinicalTrials.gov	2026-04-21