Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.2

StatusCompleted
PhaseNot applicable
Started

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Record History

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  1. Primary endpoint(s) modified Show 8 more changesShow less
    • Results posted: Oct 15, 2026
    • Trial completed
    • Primary completion date changed from estimate of Apr 1, 2027 to Mar 13, 2026
    • Start date: Feb 3, 2026 to Feb 4, 2026
    • Eligibility criteria expanded, about 16 words
    • Secondary endpoints revised (3)
    • Site details revised
    • Publications: details revised at 3 of 3 entries
  2. Primary completion date: Jan 21, 2026 to Apr 1, 2027
    • Start date: Nov 12, 2025 to Feb 3, 2026
    • Study completion date: Jan 21, 2026 to Apr 8, 2027
    v2
  3. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal role of deep brain structures in cognition. In the short term, the investigators aim to validate and characterize the effects of TI on brain activity as measured by fMRI and demonstrate its ability to focally stimulate deep brain regions without affecting overlying cortex. In the longer term, investigators aim to use these data to resolve longstanding debates about the function of deeper brain regions and lay the foundation for future clinical applications of TI for treating addiction, Obsessive-Compulsive Disorder (OCD), Parkinson's disease, and other disorders involving deep brain dysfunction. The grant supports 2 distinct aims, each of which will be evaluated through a series of independent studies.
Trial Details
NCT Number NCT07339072
Lead Sponsor Indiana University
Collaborators: National Institute of Mental Health (NIMH)
Conditions
(from sponsor)		 Healthy Volunteers
Enrollment 30 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov