Effectiveness of Multimodal Therapy for Urinary Incontinence in Pediatric Spina Bifida

Background: Overactive bladder and urinary incontinence in children have significant influence on psychosocial well-being and quality of life. The current study compared the effectiveness of the Multimodal Intervention (MMI) protocol to a Conventional Intervention (CI) in increasing urinary control, pelvic floor functioning, and quality of life. 66 adolescents (10-17 years old) were randomly divided into MMI (n=33) and CI (n=33) groups according to the inclusion criteria related to urinary incontinence. A 10-week therapeutic regime was given to every group with a 12-week post-treatment follow-up period. The key outcome measures were the number of urinary incontinence episodes per day, pelvic floor muscle electromyography (EMG) values, voiding frequency, Pediatric Quality of Life Inventory (PedsQL) items, and Pediatric Incontinence Questionnaire (PINQ) items.

NCT Number	NCT07338799
Lead Sponsor	Cairo University
Conditions	Myelomeningocele Spina Bifida, Spina Bifida, Open
Enrollment	66 participants
Start Date	2025-09-01
Primary Completion	2026-02-15 (estimated)
Study Completion	2026-02-20 (estimated)
Updated on ClinicalTrials.gov	2026-04-01