Clinical Trial

Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty

Recruiting
View on ClinicalTrials.gov →
Summary
This study aims to compare the efficacy of different doses of glucocorticoids in local infiltration analgesia (LIA) during total knee arthroplasty (TKA) through a prospective single-center randomized controlled trial, and to explore the safety and feasibility of high-dose glucocorticoids. Through this research, the investigators hope to provide an optimized solution for post-TKA pain management, improve patients' postoperative recovery and quality of life, and offer scientific evidence for pain management following TKA.
Trial Details
NCT Number NCT07337772
Lead Sponsor First Affiliated Hospital of Fujian Medical University
Conditions Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee, Anesthesia, Local
Enrollment 120 participants
Start Date 2026-02-01
Primary Completion 2028-11-01 (estimated)
Study Completion 2028-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-01-13