Clinical Trial

Opioid-Free vs Opioid-Based Anesthesia in Bariatric Surgery

Completed
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Summary
This prospective randomized controlled trial aims to compare the clinical effectiveness and safety of opioid-free anesthesia (OFA) versus traditional opioid-based anesthesia (OBA) in adult patients undergoing laparoscopic bariatric surgery. The study evaluates postoperative pain, need for rescue analgesia, incidence of postoperative nausea and vomiting (PONV), intraoperative nociception monitoring (NOL index), and patient satisfaction. A total of 60 patients were randomized into two parallel groups receiving either OFA or OBA according to standardized anesthetic protocols.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-01-06.
Trial Details
NCT Number NCT07337135
Lead Sponsor Hospital dos Lusíadas
Conditions Morbid Obesity, Postoperative Pain, Opioid Free Anesthesia, Bariatric Surgery
Enrollment 60 participants
Start Date 2023-10-02
Primary Completion 2024-04-19 (estimated)
Study Completion 2024-04-21 (estimated)
Updated on ClinicalTrials.gov 2026-02-25