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Dostarlimab, Cisplatin and Etoposide in Combination With Radiotherapy in Sandwich Sequence for Small Cell Neuroendocrine Cervical Carcinoma

StatusRecruiting
PhasePhase 2
Started2025-12-22
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 6 months later Dec 22, 2027 → Jun 22, 2028
See other at-risk trials from Chang Gung Memorial Hospital

Amendment history

2026-08-14
critical
Study Status, Sponsor/Collaborators, Arms and Interventions v2
Primary completion pushed: 2027-12-22 → 2028-06-22
Collaborators+36 characters
Taiwanese Gynecologic Oncology Group
2026-01-12
minor
Study Status, Eligibility v1
Re-verified, no change to tracked fields
2026-01-02
minor
Original filing
Add-on dostarlimab to chemoradiation with etoposide and cisplatin and radiotherapy can improve progression-free survival (PFS) compared with historical controls who were treated with chemoradiation alone in SCNECC
Trial Details
NCT Number NCT07336147
Lead Sponsor Chang Gung Memorial Hospital
Collaborators: Taiwanese Gynecologic Oncology Group
Conditions Female
Enrollment 45 participants
Start Date 2025-12-22
Primary Completion 2028-06-22 (estimated)
Study Completion 2030-12-22 (estimated)
Updated on ClinicalTrials.gov 2026-08-17