Evaluation of High-Purity Type I Collagen Biologic Wrap to Improve Function After Extensor Tendon Repair of the Hand

Tendon injuries of the hand, particularly extensor tendons, are prone to postoperative adhesions, extensor lag, and stiffness, leading to functional impairment. This multicentric randomized controlled trial evaluates whether wrapping repaired extensor tendons with a high-purity Type I collagen (HPTC) biologic membrane can reduce adhesion formation and improve functional outcomes compared with standard repair alone.

NCT Number	NCT07335653
Lead Sponsor	Adichunchanagiri Institute of Medical Sciences, B G Nagara Collaborators: Mysore Medical College and Research Institute
Conditions	Injury of Extensor Tendon of Hand, Tendon Adhesions
Enrollment	60 participants
Start Date	2025-12-05
Primary Completion	2026-02-21 (estimated)
Study Completion	2026-02-26 (estimated)
Updated on ClinicalTrials.gov	2026-04-13