Effects of Swaddling and Nesting on Pain and Stress in Newborns

This study aims to investigate the effects of swaddling and cradling methods on pain and stress levels in newborn infants receiving respiratory support. Infants receiving respiratory support in the neonatal intensive care unit may experience stress and discomfort during treatment. In this study, two different care methods that help infants feel more comfortable and secure will be scientifically compared. Only one of the Swaddling or Nesting methods will be applied to the newborns participating in the study. These methods are comfort-enhancing care practices routinely used in neonatal intensive care that do not harm the baby. The newborn's heart rate, respiratory rate, oxygen level, pain and stress symptoms will be closely and safely monitored by the healthcare team. A pain-free saliva sample will be collected to assess the newborn's stress level. It does not involve needles, does not hurt, and takes approximately 2 minutes. Pain and stress levels will be assessed in a multifaceted manner using clinical observation, physiological parameters, and saliva cortisol levels. The study aims to contribute to the strengthening of evidence-based non-pharmacological care practices in neonatal intensive care.

NCT Number	NCT07335263
Lead Sponsor	Kutahya Health Sciences University
Conditions	Stress, Non Pharmacological Intervention, Newborn Diseases
Enrollment	100 participants
Start Date	2025-02-17
Primary Completion	2026-09-06 (estimated)
Study Completion	2026-12-13 (estimated)
Updated on ClinicalTrials.gov	2026-07-28