Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation

The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.

NCT Number	NCT07334977
Lead Sponsor	Centre National de la Recherche Scientifique, France Collaborators: University Hospital, Bordeaux, Centre de la Tour de Gassies, Institute of Neurodegenerative Diseases, CNRS UMR 5293
Conditions	Stroke, Spinal Cord Injury, Able Bodied
Enrollment	45 participants
Start Date	2024-12-11
Primary Completion	2027-07-31 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2026-01-12